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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPPL1
All Species:
19.39
Human Site:
Y1135
Identified Species:
42.67
UniProt:
O15357
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15357
NP_001558.3
1258
138599
Y1135
K
T
L
S
E
V
D
Y
A
P
A
G
P
A
R
Chimpanzee
Pan troglodytes
XP_508622
1258
138671
Y1135
K
T
L
S
E
V
D
Y
A
P
A
G
P
A
R
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
Y1135
K
T
L
S
E
V
D
Y
A
P
A
G
P
A
R
Dog
Lupus familis
XP_542327
1264
138869
Y1141
K
T
L
S
E
V
D
Y
A
P
A
G
P
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6P549
1257
138955
Y1136
K
T
L
S
E
V
D
Y
A
P
G
P
G
R
S
Rat
Rattus norvegicus
Q9WVR3
1257
139124
Y1136
K
T
L
S
E
V
D
Y
S
P
G
P
G
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517954
539
59681
Q429
S
M
I
G
S
T
A
Q
Q
F
L
T
F
L
S
Chicken
Gallus gallus
XP_426250
1017
112344
E907
L
P
Q
T
E
A
G
E
A
V
Q
G
V
Q
G
Frog
Xenopus laevis
Q6P4S2
1019
115278
E909
A
R
M
R
A
A
P
E
T
Q
N
S
M
D
H
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
D1133
G
G
A
S
A
L
D
D
Q
S
C
S
V
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
P1125
R
D
V
A
L
P
P
P
L
P
A
R
P
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.4
96.3
N.A.
95.8
95.5
N.A.
31.7
42.9
39.3
65.8
N.A.
N.A.
N.A.
N.A.
32.5
Protein Similarity:
100
99.6
98.7
97.3
N.A.
96.8
96.5
N.A.
35.4
55.4
53.3
75.9
N.A.
N.A.
N.A.
N.A.
49.5
P-Site Identity:
100
100
100
93.3
N.A.
66.6
60
N.A.
0
20
0
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
66.6
66.6
N.A.
6.6
26.6
6.6
26.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
19
19
10
0
55
0
46
0
0
28
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
64
10
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
64
0
0
19
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% F
% Gly:
10
10
0
10
0
0
10
0
0
0
19
46
19
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
55
0
10
10
0
0
10
0
10
0
0
19
10
% L
% Met:
0
10
10
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
10
0
0
0
10
19
10
0
64
0
19
46
0
0
% P
% Gln:
0
0
10
0
0
0
0
10
19
10
10
0
0
10
10
% Q
% Arg:
10
10
0
10
0
0
0
0
0
0
0
10
0
19
37
% R
% Ser:
10
0
0
64
10
0
0
0
10
10
0
19
0
10
28
% S
% Thr:
0
55
0
10
0
10
0
0
10
0
0
10
0
0
0
% T
% Val:
0
0
10
0
0
55
0
0
0
10
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _